Biotin receptor expression
WebDec 9, 2024 · One widely studied group of receptors are non-catalytic tyrosine-phosphorylated receptors (NTRs), also called immunoreceptors, which are the largest group of receptors expressed on leukocytes [ 1 ]. … WebPeroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated nuclear receptor that regulates cellular lipid and glucose metabolism and also plays an inhibitory role in various cancers. However, the role of PPARγ in hepatocellular carcinoma (HCC) remains controversial. This study aimed to investigate the prognostic value of PPARγ in HCC and …
Biotin receptor expression
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WebNov 16, 2024 · It also showed preferential uptake on HepG2 human hepatocarcinoma cells (with higher biotin receptor expression) rather than Chinese hamster ovary (CHO) cells (with lower biotin receptor expression). Upon irradiation, it caused photocytotoxicity with an IC 50 value down to 0.1 μm on HepG2 cells. WebSep 25, 2014 · These results showed that biotin-conjugated NPs could improve the delivery of PTX into cancer cells via interactions with overexpressed biotin receptors. Chen et …
WebThe new vector was able to mediate biotin receptor (BR)‐selective transfection and was tested on five cell types with different BR expression levels.
Biotin is an essential vitamin playing its role in cellular carbohydrate, amino acid and lipid metabolism.1 Unlike bacteria, mammalian cell machinery does not produce biotin, therefore biotin is supplemented exogenously.1 There is evidence that expression of biotin receptors (BRs) is correlated with cancer.2 … See more This work received financial support from Agence Nationale de la Recherche (BrightRiboProbes, ANR-16-CE11-0010-01/02) and ERC … See more In conclusion, we designed and synthesized a series of biotinylated fluorogenic probes for biotin receptors overexpressed in cancer cells. We focused on the molecular design of dimeric squaraines … See more WebAssessment of the Expression Level of Biotin Receptor in Cancer Cell Lines Using Fluorescent Probe 7. Although Russell-Jones et al. reported a dozen cell lines …
WebAn indirect biotin-free system for the detection of various primary antibodies (Ultraview Universal Diaminobenzidine kit) was used for detection. The slides were then counterstained with hematoxylin (Harris). ... Case #30 shows moderate to weak ER expression. ER indicates estrogen receptor; IHC, immunohistochemical; SD, surface decalcification ...
WebApr 14, 2024 · 3.1 Enrichment of SNO proteins using biotin switch technology. To clarify the role of AA in the biotin switch method, SW 480 cells were used to conduct a Western blot experiment to enrich endogenous SNO proteins. The results confirmed that AA obviously reduced the extent of SNO reducing the -SNO bonds of proteins to -SH bonds . AA was … five9 cx summitWebNov 28, 2015 · Adaptor protein sorting nexin 17 interacts with the scavenger receptor FEEL-1stabilin-1 and modulates its expression on the cell surface. ... using TSA Biotin System(NEN Life Science Products, MA, USA) streptavidinconjugate Alexa Fluor 488 (Invitrogen). 554 Biochimicaet Biophysica Acta 1803 (2010) 553–563 role … can indigestion cause pain in rib cageWebHerein, we report a GSH activated biotin-tagged NIR probe P6 ( Figure 1) that exhibits sensitive and specific imaging features for cancer cells. Probe P6 can be recognized and transported into cancer cells by tumor specific biotin receptors and efficiently be triggered by GSH to release the fluorophore 4, thereby making various cancer cells to ... five9 desktop agent downloadWebSep 25, 2014 · Somatostatin receptors (SSTRs), members of the superfamily of G-protein coupled receptors (GPCRs), are widely expressed in a variety of tumors and cancer cell lines, including small cell lung cancer [32], neuroendocrine tumors [33], prostate cancer [34], breast cancer [35], colorectal carcinoma [36], gastric cancer [37] and hepatocellular … five 9 dashboard agentWebFeb 13, 2012 · These results suggest that CAR expression in PBL could be reliably detected using a protein L based FACS assay. In this study, we established the suitability of protein L staining as a novel and general reagent for the determination of CAR expression in PBL. Furthermore, staining is rapid and uses fewer reagents than comparable protocols. five9 customer serviceWebMay 25, 2024 · Biotin is a water soluble, readily cell permeable, and a brain penetrant vitamin (vitamin H or B7) that is required as a co-factor for several enzymes involved in … five 9 dialer downloadWebApr 14, 2024 · Materials and methods. In this study, the protein extracts of human tissues and cell lines were treated by biotin switch technology and magnetic beads enrichment. … five9 earnings transcript