Cl4-tcr
WebLymphocytes from the thymus (TH), spleen (SP) and mesenteric lymph nodes (MLN) of CL4-TCR, VILLIN-HA/CL4-TCR and VILLIN-HA transgenic mice were stained for the … WebApr 13, 2024 · 现货发售 Claudin家族再添新成员：全长Claudin 4蛋白. 来源： 北京百普赛斯生物科技股份有限公司 2024-4-13 访问量：35 评论 (0) 导读. 转移是指由于癌细胞扩散从原发部位到达其他部位继续生长的过程，也是导致癌症患者的死亡率居高不下的主要原因。. 转移 …
Cl4-tcr
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WebNov 15, 2004 · BALB/c mice were inoculated with AB1-HA tumor cells on day 0, then treated with anti-CD40 mAb or PBS on days 14, 16, and 19. On day 21, 1 × 10 7 CFSE-labeled, naive CD8 + CL4-TCR transgenic T cells were adoptively transferred into tumor-bearing recipients and DLN cells were harvested 3 days later and stained for CD8 in conjunction …
Web105 splenocytes from CL4-TCR mice were transferred into VILLIN-HA mice on day 0. This transfer resulted in a mild enterocolitis and a maximum of 10% loss in body weight within … WebDec 18, 2024 · T cell receptor (TCR) Tg mice are extremely useful in studying T cell-mediated immune responses because the majority of T cells in these mice express …
WebOct 15, 2012 · Compared with controls, the GFAP-HA × CL4-TCR mice exhibited a selective EGC depletion (34% and 72%) and apoptosis (4% and 14.5%) in the myenteric and submucosal plexus, respectively. These EGC abnormalities were associated with massive intestinal inflammation involving CD8 + T cell-mediated cytotoxic autoimmunity. This … WebJan 31, 2008 · (referred to as GFAP-HA hereafter). HA peptides are expressed by EGCs and recognized by CD8 T cells that express a T-cell receptor (TCR) specific for K d:HA …
Webby naïve CL4 CD8+ T cells To investigate the role of CD8+ T cells in anti-tumour immunity, our lab utilized CL4 TcR transgenic mice in which virtually all the CD8 + T cells express the Vα10/Vβ8.2 TcR transgene13. These CL4 T cells are able to recognize the dominant Kd-restricted epitope of the Influenza virus A/PR/8 haemagglutinin (HA ...
WebJul 1, 2010 · A total of 5 × 10 5 splenocytes from CL4-TCR transgenic mice were injected i.v. into naive VILLIN-HA recipients on day 0. Mice were injected again with 1 × 10 7 … door mat with nameWebTo dem- onstrate that the tetramers bind the appropriate receptors, LN cells from CL4 TCR transgenic mice were stained. Tetramer-positive cells represented 80% of the transgenic … city of maxeys gaWebMay 21, 2024 · The T cell receptor (TCR) of T cells from CL4 TCR transgenic mice recognizes the HA peptide 518 to 526 (IYSTVASSL) as restricted by H2-K d. Upon adoptive transfer into RencaHA tumor-bearing mice, CL4 CTL infiltrate the tumor and acquire a suppressed phenotype ( 7 ). door mat with treesWebTo follow autoreactive T cells during AIH, we adoptively transferred HA--specific Cl4-TCR and 6.5-TCR T cells into Ad-Cre infected -Rosa26-HA mice. Alternatively, Rosa26-HA mice have been crossed with TCR transgenic mice that were infected with Ad-Cre to break hepatic tolerance and induce the expression of the HA antigen as a hepatic self-antigen. doormerica hardware warrantyWebTo follow autoreactive T cells during AIH, we adoptively transferred HA--specific Cl4-TCR and 6.5-TCR T cells into Ad-Cre infected -Rosa26-HA mice. Alternatively, Rosa26-HA … door mechanical armWebFigure Legend Snippet: (A) CFSE-labeled HA-specific CD8 + CD25 − T cells from CL4-TCR transgenic mice were adoptively transferred into VILLIN-HA and BALB/c recipient mice. At day 4 after adoptive transfer cells from the MLN of recipient mice were isolated and stained for the expression of CD8 and Foxp3. door measurements for wheelchairsWebMutation details : Tcra and Tcrb cDNAs were isolated from Clone-4, a CTL line derived from a B10.D2-Hc 1 H2 d H2-t18 c /nSnJ mouse immunized with influenza virus A/PR/8. A … city of maxton