Cst plin2
WebMar 29, 2024 · The PLIN2-intramuscular triglyceride association was reduced postexercise. PLIN2-PLIN5 proteins were all more abundant in women than in men (p = 0.037 and p < 0.0001, respectively), consistent with higher intramyocellular lipid content observed in female skeletal muscle. High PLIN2 protein level is associated with colorectal cancer. WebResults The algorithm for NASH using PLIN2 mean florescence intensity (MFI) combined with waist circumference, triglyceride, alanine aminotransferase (ALT) and presence/absence of diabetes as covariates had an accuracy of 93% in the discovery cohort and of 92% in the validation cohort. Sensitivity and specificity were 95% and 90% in the …
Cst plin2
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WebSep 26, 2024 · Lipid-laden fibroblasts (lipofibroblasts) express the Perilipin 2 (Plin2) gene … WebNov 18, 2014 · Although perilipin 2 (Plin2) has been shown to bind lipids with high affinity, the Plin2 lipid binding site has yet to be defined. This is of interest since Plin2's affinity for lipids has been suggested to be important for lipid droplet biogenesis and intracellular triacylglycerol accumulation. To define these regions, mouse Plin2 and several ...
WebFeb 15, 2016 · Perilipin2 (Plin2), also known as adipose differentiation-related protein (ADRP), or adipophilin, is a member of the PAT family involved in lipid droplet (LD) formation in the liver and peripheral ... WebMar 29, 2024 · Upregulated monocyte expression of PLIN2 is associated with early arterial injury in children with overweight/obesity. Pisano E, et al. Atherosclerosis, 2024 Jun. PMID 34044206. Correlation of perilipin 2 and lipid metabolism in elective cesarean section and vaginal delivery: a prospective study with oxidative and apoptotic pathways.
WebApr 28, 2024 · Moreover, PLIN2 knockout mice are resistant to diet-induced obesity, fatty liver disease and alcohol-induced steatosis, suggesting that PLIN2 is responsible for lipid accumulation, particularly in the liver [41, 42]. Taken together, these studies suggest that PLIN2 promotes LD formation and thereby protects TG from lipolysis. WebMay 15, 2014 · Background Perilipin 2 (Plin2) is a lipid droplet protein that has roles in both lipid and glucose homeostasis. An increase in Plin2 in liver is associated with the development of steatosis, glucose intolerance, and …
WebNov 23, 2024 · Importantly, we found that the percentage of Plin2 + microglia was much higher in apoE4 mice (26%) compared to apoE2 (9%) and apoE3 (13%) mice (Fig. 6D). We next validated genes associated with lipid transport and metabolism and showed that Lpl and Apoc1 were altered in an apoE isoform-dependent manner.
WebMay 15, 2014 · Perilipin 2 (Plin2) is a lipid droplet protein that has roles in both lipid and glucose homeostasis. An increase in Plin2 in liver is associated with the development of steatosis, glucose intolerance, and … grabbing shirtWebDec 13, 2024 · For example, PLIN2 and PLIN3 expression predominates in mouse liver, muscle cells , and pancreatic islets , whereas PLIN1 is significantly upregulated as preadipocytes mature into adipocytes . Perilipin protein function has been studied primarily in rodents, and, for example, PLIN2 ( 17 , 18 ) or PLIN3 ( 19 ) null mice are protected … grabbing snake by neck dreamWebADFP may be a possible new marker for the identification of specialized differentiated … grabbing shoulderWebMay 6, 2024 · A recent report shows that cardiac overexpression of Plin2 result in massive myocardial steatosis suggesting that Plin2 stabilizes LDs. In this study, we hypothesized that deficiency in Plin2 ... grabbing someone by the chinWebAug 1, 2012 · The plin2-EYFP or plin1ΔC-EYFP fragment was shuttled into the transformation vector pUAST-attB through EcoRI and XbaI sites. All constructs requiring PCR amplification were confirmed by sequencing. All quantitative RT-PCRs were performed on an ABI PRISM 7900HT real-time cycler (Applied Biosystems) using Power SYBR … grabbing someone by the armWebJul 12, 2024 · Herein, we show that PLIN2 is the most abundant protein on the lipid … grabbing some lunchWebSep 9, 2024 · A recent study showed that the generation of ROS can increase perilipin 2 (Plin2) expression in HepG2 cells. Some evidence has also demonstrated the association between Plin2 expression and renal tumors. However, the underlying mechanism of Plin2 in I/R-induced acute kidney injury (AKI) remains elusive. Here, using a mouse model of I/R … grabbing someone by the hair