Cyp6a2
WebMar 23, 2009 · These results show that CYP6A2 catalyzes the metabolism of organophosphorus insecticides and they implicate Cyp6a2 overexpression in metabolic resistance. The Cyp6a2 gene appears to be a suitable model for a genetic analysis of the phenobarbital induction process. Figures References Related Details To cite this article: WebCyp6a2 expression varies considerably between different strains. For instance, higher RNA levels are found in the 91R strain (insecticide resistant) when compared to the 91C strain …
Cyp6a2
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WebNov 24, 2024 · Overexpression of functional Cyp6a2 was consistently associated with DDT resistance. Luciferase reporter gene assays revealed that an intact Nrf2/Maf binding site … WebMay 1, 2000 · Europe PMC is an archive of life sciences journal literature. This website requires cookies, and the limited processing of your personal data in order to function.
WebFeb 15, 2024 · Compared to other alleles, Cyp6a2 Canton-S-1 lacks a 15bp fragment in the 5' core promoter region. This region forms part of a canonical binding site for the Nrf2/Maf heterodimer. The Cyp6a2 Canton-S-1 allele also has a 513-bp insertion of a 17.6 element in the 3' UTR. (Wan et al., 2014) WebMay 2, 2000 · The expression of two second chromosome-linked cytochrome P450 genes, Cyp6a2 and Cyp6a8, of Drosophila melanogaster was measured in various strains. Six …
WebMay 27, 2024 · In addition, we knew that CYP6A2 was able to metabolize ethoxycoumarin as well as diazinon, aldrin, and deltamethrin (, Amichot et al., unpublished data). Although we did not demonstrate that Cyp6a2 was an effector of adaptation to the for-controlled environment, we demonstrated here that for was able to modulate the expression level of … The psiCHECK-2 dual fluorescent reporter system (Promega, Madison, WI, USA) was used to determine any interaction of miR-310s with putative target binding sites in Cyp6g1 and Cyp6g2. The psiCHECK-2 system incorporates Renilla luciferase as a reporter gene and firefly luciferase as a control to normalize for … See more The DDT-susceptible Canton-S, the low-level DDT-resistant 91-C, and the highly DDT-resistant 91-R strains of Drosophila have been … See more First-strand cDNA synthesis was performed using the miScript II RT kit (Qiagen). Each synthesized cDNA sample was then used as a template for RT-qPCR reactions using the miScript SYBR Green PCR Kit (Qiagen) … See more A set of mirVana mimics were synthesized for miR-310, miR-311, miR-312, and miR-313 by Invitrogen (Ambion, Life Technologies) at a … See more One-day-old female 91-R (90 flies per each injection) were injected separately with miR-310s mimics, NCsiRNA, and DEPC-water using … See more
WebAlthough Cyp6a2 has been observed to be overexpressed in many 4,4′-dichlorodiphenyltrichloroethane (DDT)-resistant strains of Drosophila melanogaster, how …
Web目的:建立大鼠体外肝微粒体孵育体系，分别以非那西丁和双氯芬酸作为CYP1A2和CYP2C9的特异性探针药物，通过高效液相色谱法(High Performance Liquid Chromatography, HPLC)分别测定大鼠肝微粒体体系中探针药物非那西丁和双氯芬酸的代谢产物对乙酰氨基酚和4-羟基双氯芬酸的浓度，计算肝微粒体中非那西丁和双 ... flag ceremony cscWebDegenerate primers corresponding to conserved amino acid sequences in three insect P450s, Musca domestica (CYP6A1), Drosophila melanogaster (CYP6A2) and Papilio polyxenes (CYP6B1), were used to clone xanthotoxin-induced P450 transcripts from P. glaucus larvae by a reverse transcription-polymerase chain reaction (RT-PCR) strategy. flag center richmond vaWebAlthough Cyp6a2 has been observed to be overexpressed in many 4,4′‐dichlorodiphenyltrichloroethane (DDT)‐resistant strains of Drosophila melanogaster, how Cyp6a2 is regulated and whether its overproduction confers DDT resistance remain elusive. flag ceremony clip artWebSep 4, 2013 · Molecular analysis identified five Cyp6a2 alleles (Cyp6a2 Canton −S‐1, Cyp6a2 Canton −S‐2, Cyp6a2 91‐C, Cyp6a2 91‐R and Cyp6a2 Wisconsin − WD) from four D. melanogaster strains, notably differing in the presence or absence of an intact Nrf2/Maf (a transcription factor) binding site in the 5′‐promoter core region, a ‘G1410 ... flag case with medal displayWeb17.3.1.4 CYP2A6. CYP2A6 is a member of the cytochrome P450 superfamily and is expressed predominantly in hepatic cells, with some expression in specialized … flag certificate armyWebFeb 23, 2024 · Cyp6a2 provided by FlyBase Official Full Name Cytochrome P450 6a2 provided by FlyBase Primary source FLYBASE:FBgn0000473 Locus tag Dmel_CG9438 … cannot set time zone automatically windows 10Weba.有助于个体化给药b.有利于诊断特殊疾患c.改变降脂治疗观念d.列为医药卫生行政决策的依据e.证明一些常规治疗方法是盲目;“美国心脏病学院与美国心脏协会2014年颁布了(2013版成人降胆固醇治疗降低动脉粥样硬化性心血管疾病风险指南》，强调他汀类药物在降低急性冠脉综合征风险方面的获益 ... flag ceremony for deceased veteran