Extensively distributed
WebApr 19, 2024 · Parallel Processing Example. It's fairly easy to identify a parallel processing example, considering most people are constantly using this process to understand the world around them and respond ... WebConsistent with its lipophilic amine character, paroxetine is extensively distributed into tissues. Its plasma protein binding at therapeutically relevant concentrations is about 95%. Paroxetine is eliminated by metabolism involving oxidation, methylation, and conjugation. All of these factors lead to wide interindividual variation in the ...
Extensively distributed
Did you know?
WebNov 7, 2024 · Plants-derived Polyphenols represent a major class of compounds extensively distributed in plants. Number of polyphenols have demonstrated antidepressant activity, among which berberine, piperine, curcumin, naringenin, ascorbic acid and ginsenosides are extensively evaluated. The medicinal plants and their derived … WebAug 4, 2013 · Effect of Protein Binding on the Apparent Volume of Distribution • The extent of drug protein binding in the plasma or tissue affects V D. Drugs that are highly bound to plasma proteins have a low fraction of free drug • The plasma protein-bound drug does not diffuse easily and is therefore less extensively distributed to tissues 15.
WebDigoxin is extensively distributed in the tissues, as reflected by the large volume of distribution. High concentrations are found in the heart and kidneys, but the skeletal … WebFeb 15, 2024 · Distribution: Ondansetron and its metabolites are extensively distributed in tissues. The apparent volume of distribution(Vd) at a steady state is approximately 1.8 L/kg. Ondansetron crosses the blood-brain barrier to a lower extent, with the CSF concentration only about 10%-15% of the plasma concentration in human volunteers.
WebV d can be used as a volume (e.g., L), but is more commonly normalized by dividing by the total body weight, thus giving the units L/kg (kg of body weight) or mL/kg. V d is not an … WebApr 11, 2024 · Although drosophilids have been extensively studied in laboratories worldwide, their ecology is still relatively poorly understood. This is unfortunate because some species are currently expanding their geographic distribution and infesting fruit crops. Here, we investigated the relationship between drosophilids and potential plant hosts in a …
Web672 other terms for extensively- words and phrases with similar meaning
WebExtensively Distributed synonyms - 49 Words and Phrases for Extensively Distributed. widely disseminated. widely distributed. widely spread. broadly dispersed. broadly … lamparas atexWebBackground: Multidrug/extensively drug-resistant tuberculosis (M/XDR-TB) is a major public health problem, and early detection is important for preventing its spread. This study … jess\\u0026coWebThe tissue distribution and pharmacokinetics of 3H-budesonide were studied in the mouse after intravenous administration. The drug was rapidly (t1/2 alpha = 0.062 hrs) and extensively distributed into tissues and organs (V beta = 20.3 l/kg and Vss = 9.4 l/kg). The short elimination half-life (t1/2 beta = 1.55 hrs) and high blood clearance (Cl ... jesstvWebAug 5, 2024 · Exosomes are described as nanoscale extracellular vesicles (EVs) secreted by multiple cell types and extensively distributed in various biological fluids. They contain multifarious bioactive molecules and transfer them to adjoining or distal cells through systemic circulation, participating in intracellular and intercellular communication, and ... jess\\u0026jamie.co.ukWebV d can be used as a volume (e.g., L), but is more commonly normalized by dividing by the total body weight, thus giving the units L/kg (kg of body weight) or mL/kg. V d is not an actual measurable volume. Instead, it represents the apparent total volume into which the drug is distributed, if the concentration in the tissues is the same as the concentration in … jess\u0026coWebThe mean steady-state apparent volume of distribution of tamsulosin hydrochloride after ... Tamsulosin hydrochloride is extensively bound to human plasma proteins (94% to 99%), primarily alpha-1 acid glycoprotein (AAG), with linear binding over a wide concentration range (20 to 600 ng/mL). The results of two-way : in vitro: studies indicate ... lampara sb 900WebSynonyms for Widely Distributed (other words and phrases for Widely Distributed). Log in. Synonyms for Widely distributed. 94 other terms for widely distributed- words and … jess \u0026 jane tops