Web1 okt. 1990 · Determination by photoaffinity labelling of the hydrophobic part of the binding site for acyl-CoA esters on acyl-CoA-binding protein from bovine liver Biochem J . 1990 Oct 1;271(1):231-6. doi: 10.1042/bj2710231. Web16 feb. 2015 · Photoaffinity labeling (PAL) using a chemical probe to covalently bind its target in response to activation by light has become a frequently used tool in drug …

Photo-affinity labelling and biochemical analyses identify the …

WebPhotoaffinity labelling of mitochondrial proteins, action of potential dissipating drugs, and competitive staining Influence of trans-membrane potential and of hydrophobic interactions on dye accumulation in mitochondria of living cells. Web10 okt. 1981 · Photoaffinity labeling of a mitochondrial hydrophobic protein by an anisotropic inhibitor of energy transduction in oxidative phosphorylation. The … syfy computer

Determination by photoaffinity labelling of the hydrophobic …

WebPhotoaffinity labeling (PAL) is another powerful biochemical technique for the investigation of ligand-protein interactions frequently probed in drug discovery to isolate and identify … Webthe hydrophobic F1 NH2 terminus, consisting of about 20 amino acids, into the target membrane (1, 3, 5, 6). Hydrophobic protein-lipid interactions (7-10) and some proteins that cause membrane fusion (11, 12) 'have been investigated by usinIg photoaffinity labels. Such studies typically involve labeling of both protein and lipid after an WebRobert L. Macdonald, Matt T. Bianchi, in Encyclopedia of the Neurological Sciences, 2003 Functional Domains for Benzodiazepine Action. Photoaffinity labeling with [3 H]flunitrazepam identified H102 in bovine α 1 (H101 in rat, which is also present in α 2, α 3, and α 5), and its importance was shown by mutagenesis.Replacement of the H in the α 1 … syfy east schedule