WebHydralazine, propylthiouracil, and procainamide can cause a systemic lupus erythematosus (SLE)-like syndrome, which is a type III hypersensitivity reaction. The syndrome may be mild (with arthralgias, fever, and rash) or fairly dramatic (with serositis, high fevers, and malaise), but it tends to spare the kidneys and central nervous system. WebPharmacodynamics. Hydralazine interferes with calcium transport to relax arteriolar smooth muscle and lower blood pressure. 19 Hydralazine has a short duration of action of 2-6h. 10 This drug has a wide therapeutic window, as patients can tolerate doses of up to 300mg. 19 Patients should be cautioned regarding the risk of developing systemic lupus …
If you have allergies, you may want to avoid this type of medication
WebNov 1, 2003 · The majority (75 to 80 percent) of adverse drug reactions are caused by predictable, nonimmunologic effects. 1 The remaining 20 to 25 percent of adverse drug events are caused by unpredictable ... WebHydroxyzine is an antihistamine with anticholinergic (drying) and sedative properties used to treat itching caused by allergic reactions. It is also used to treat anxiety and tension, and for inducing sedation prior to or after anesthesia. Hydroxyzine also is used to treat nausea, vomiting, and alcohol withdrawal.. Hydralazine is an antihypertensive medication used to … litepro edge crankset
Clinical Characteristics of Hydralazine-induced Lupus - PubMed
WebDec 12, 2024 · Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble … Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Hydralazine may cause serious side effects. Call your doctor at once if you have: 1. chest pain or pressure, pain spreading to your jaw or shoulder; 2. fast or pounding … See more Hydralazine is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries. Hydralazine … See more Follow all directions on your prescription label. Do not take hydralazine in larger or smaller amounts or for longer than recommended. Your … See more You should not use hydralazine if you have coronary artery disease, or rheumatic heart diseaseaffecting the mitral valve. See more You should not use hydralazine if you are allergic to it, or if you have: 1. coronary artery disease; or 2. rheumatic heart diseaseaffecting the mitral valve. To make sure hydralazine is … See more WebMar 31, 2014 · A case report of hydralazine-induced skin reaction: Probable toxic epidermal necrolysis (TEN) Clinical awareness with close monitoring is important for the … litepro edge